Инфекгил IV

Description

 

Compound:

Metronidazole IP – 500 mg

Infusion base – 100 ml

Sterile, apyrogenic, ready-to-use solution for intravenous administration

 

Package:

glass or plastic bottle 100 ml / infusion bag

Sterile packaging with a seal against opening

Comes with full labelling and instructions for use.

 

Infekgil IV Review:

Infekgil IV is a parenteral form of metronidazole, an antimicrobial agent of the nitroimidazole group, used primarily for the treatment and prevention of anaerobic bacterial and protozoal infections. It is effective against a wide range of anaerobes and is especially valuable in intra-abdominal, gynecological, dental and colorectal infections.

 

Key Features and Benefits:

• Broad spectrum of anaerobic antibacterial and antiprotozoal activity
• Ready to use solution for infusion – no dilution required
• Rapid onset of action when administered intravenously
• Widely used for preoperative and postoperative prophylaxis
• Useful in mixed aerobic-anaerobic infections

 

Mechanism of action:

Metronidazole disrupts DNA synthesis in susceptible organisms, resulting in cell death. Its selective toxicity to anaerobic organisms makes it ideal for targeted therapy without significantly affecting normal flora.

 

Indications:

• Intra-abdominal infections (peritonitis, abscess)
• Gynecological infections (endometritis, pelvic abscess)
• Septicemia caused by anaerobic bacteria
• Surgical prophylaxis (colorectal, abdominal, gynecological)
• Dental infections
• Protozoal infections (eg, amebiasis, giardiasis – when intravenous administration is indicated)

Dosage and method of administration:

Usual adult dose: 500 mg intravenously every 8 hours.

Infuse for 20-60 minutes

Dosage and duration may vary depending on the severity of the infection and kidney/liver function.

 

Precautions:

Use with caution in patients with hepatic impairment.

Monitor for neurotoxicity during prolonged or high-dose therapy.

Avoid drinking alcohol during and for at least 48 hours after treatment (risk of disulfiram-like reaction).

 

Contraindications:

Known hypersensitivity to metronidazole or other nitroimidazoles

First trimester of pregnancy (unless absolutely necessary)

Patients with active CNS disease

 

Possible side effects:

• Nausea, metallic taste
• Headache or dizziness
• Peripheral neuropathy (rare)
• Infusion site reactions (pain, swelling)
• Convulsions (rarely with high doses/long term use)

 

Storage instructions:

• Store at temperatures below 25°C
• Do not freeze
• Use before expiration date
• After opening, use immediately or discard any unused portion.

 

Infekgil IV – Reliable protection against anaerobic infections with fast and effective intravenous therapy.

 

Frequently Asked Questions – Infegyl IV (Metronidazole Infusion) 

Q1: What types of infections does Infecil IV treat?

A: It is effective against anaerobic bacterial infections, pelvic and abdominal infections, and is often used for surgical prophylaxis.

 

Question 2: How is Infekgil IV administered?

A: It is given intravenously over 20 to 60 minutes by a health care professional, usually in a hospital or clinic.

 

Question 3: Can Infecil IV be used during pregnancy?

A: Not recommended in the first trimester unless absolutely necessary. Consult your doctor before use.

 

Question 4: Why should I avoid drinking alcohol while taking Metronidazole?

A: Alcohol can interact with metronidazole and cause nausea, vomiting, seizures, and headaches (disulfiram-like reaction).

 

Question 5: How quickly does Infecil IV start working?

A: It begins to work quickly after infusion, often within 1 to 2 hours, depending on the severity of the infection.